yes they can. the fda says a drug can be 15% plus or minsus the dose.lets say a regler sinemet has a 100mg of ldopa. that meens it could cotain up to 115mg of ldopa or as little as 85mg of lodopa. the outher problum is how guik they disolve what i would sujest is disolve the sinemet in ginger ale like 1/2 a glass and try taking it that way. a great trick i usedin the past is to get a 6 pack of ginger ail in the small bottles put eather 2 25/100 or 1 25/250 sinemet in the bottle take a sip every 1 2hrs wicth is 20 to 30mg a dose the trick is to dose yourself every 1 to 1 and 1/2 hours. keep it cool. its good for about 24 hours. tony ----- Original Message ----- From: "patandpaula" <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, July 02, 2002 12:43 PM > can anyone please tell me if the generic form of sinimet could possibly be less effective than sinimet brand itself? thank you so much paula > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn