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Connie, after 2 glutathione 250 mg pills I noticed less stiffness, easier to walk, get up from a chair, etc. Am still taking it, but like my experience with Sinemet, it doesn't seem to make a great deal of difference after first dose. Strange. Rayilyn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn