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I am not a medical expert by any means, but I did a search of PubMed for articles related to PD and SAMe. I found this abstract rather interesting. Obviously this study is for rats, but I think it points out that caution should be used when looking at any supplements. "Tremor is the most visible symptom of Parkinson's Disease (PD), and should be the appropriate parameter in models for its evaluation. Lack of reliable PD tremor models and methods to distinguish tremors from nontremor movements means that nontremor behavior such as rotation following basal ganglia damage are mostly used. Our laboratory has shown that S-adenosyl-methionine (SAM) injections into the brain of rats reliably produced tremors, rigidity, hypokinesia, and abnormal posture. Thus, SAM-induced tremors, when distinguished from nontremor activities, has the potential as a model for testing anti-PD agents" ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn