Hi Cheryl, My husband has PD and was put on Sinemet immediately after being diagnosed. In doing research and reading all I can I find that those in the know say to hold off as long as you can before starting Sinemet. There are some early type meds that you can take that do not cause the problems of Sinemet. Sinemet is the type of med. that can cause problems as well as help. The sooner you start on it the more you need sooner. Find or write for the book, "Brain Recovery.com" by David Perlmutter, M.D. He is well respected in the medical field and is a certified Neurologist. In his book (fairly small paper back)he lists medication for PD that are supplement types. My husband is taking Co.Q10 (150 mg. )and has shown improvement since he started on it. Five or six studies are currently being conducted at Medical Schools to try to determine if Co.Qu10 is helpful in PD. It is available in drug stores (Walmart) .He is actually better today than he was when first diagnosed. He does take a low dose of Sinemet and Mirapex. He has been diagnosed for six years. He is taking all the recommended items as listed in the book accept the glutathione. There is controversy as to whether the oral is effective. Perlmutter says no. Permutter has a web site. Good luck. Do some research before you get started on the meds. Vera Brandt ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn