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My pharmacist told me to be careful not to take B6 while taking Sinemet as it interferes with the absorption of B6 into the brain.  I was curious and decided to investigate for myself. Sure enough he was right.  If you look up B6 on the internet a warning is listed about taking it while taking drugs for Parkinsons.  Likewise if you look up Sinemet it gives a warning about B6.  My understanding after further conversations with my pharmacist is that it is only B6 that is a problem.  Other B vitamins such as B12 are fine.
You might also wnt to watch out for tyrosine.  It is supposed to interfere with the absorption of sinemet too.  Just FYI.
Debra  

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