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I was diagnosed with PD four years ago It began with a slight tremor in my left leg. I am on Mirapex and Sinemet. I also have rheumatoid arthuritis and take methotrexate for that along with a low dose of prednisone. I have found Mirapex to work well but feel the Sinemet is also needed. I have experienced most of the symptoms you have and can only tell you to keep close contact with you neuro so that he/she can keep up with the need for changes in your medication. Be sure to eat healthy and rest often. I do not climb up on ladders or chairs and walk slowly being sure where I step. Many advances are being made in the treatment of Parkinsons. Michael J. Fox has been a real advocate for all of us. There are bright prospects for future use of stem cells and new medications and treatments appear all the time. Get all the booklets and material that you can and keep abreast and informed. Do you have family nearby and friends? Be sure to make daily contact with any and/or all of them. They will help you keep a cheerful spirit and it will be a comfort for you. That is really the bottum line and as hard as it may seem sometimes, there are always things to be thankful for. Keep in touch with the wonderful people on our list. Someone will be there to help you 24 hours a day. I know, they helped me and continue to do so. Marilyn, Florida ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn