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>I am in the process of reading the actual study for the recent CoQ10 test. >Some interesting things so far: >People were excluded from the study for the following reasons: >1. "The use of drugs known to interfere with mitochondrial activity." I >would like to avoid these all the time--how do we find out drugs on this >list? > >2. "The use of methylphenidate hydrochloride, cinnarizine, reserpine, >amphetamines, or monoamine oxidase-A inhibitors within 6 months before the >baseline visit." I havent done my research yet to determine if this >restriction is for positive or negative reasons i.e. could influence outcome >of the subject patient in a positive or negative manner. > >3. "An unstable dosage of drugs active in the central nervous system (e.g. >anxiolytics, hypnotics, benzodiazepines, and anti-depressants) during the 60 >days before the baseline visit." HOw would this impact the outcome of >experiment? > >Another interesting point: "The wafers with active study drug contained 300 >mg of coenzyme Q10 and 300 IU of vitamin E as a lipophilic carrier" >Hmmmmm--i dont remember this coming up in the discussion earlier. I dont >think the Vitaline CoQ10 wafers contain any vitamin E! > >Also: "Patients were asked to take a standard daily multivitamin without >minerals but no other supplemental vitamins." > >And finally: "A blood sample was again drawn at the final visit for >evaluation of platelet mitochondrial function." Could a simple blood test >be used to help diagnose PD? > >Bob > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: mailto:[log in to unmask] >In the body of the message put: signoff parkinsn HELLO BOB: I SPOKE TO VITALINE (1-800 287-5972). CURRENT SUPPLY OF WAFERS DON'T CONTAIN VIT E. ON ABOUT NOV 15TH THEY'LL BE ADDING 300 IU OF E TO EACH WAFER TO DUPLICATE THAT USED IN STUDY. RALPH ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn