There shall always be statistical variation. From the differential effect
on the dose of CoQ10, it appears to me that even a low dose could be
beneficial One reason why there is so much variation in the effect would
be:
the different individuas may be at a different stage f the disease, i.e,
some slighly more advanced than others.
We all know that PD is a "designer disease", although I know I didn't
have anything to do with the design of my disease.
I started taking 60 mg x 3 a day abut two months ago. I find great
improvement. I am also taking oral L-glutathione 200 mg first thing in the
morning. I was diagnosed two yeas ago with PD in addition to ET. I think I
have had PD symtoms for about 30 years; but, they were so mild I did not
even suspect there was something wrong with me. Till todate I have been
sucessfully avoiding taing sinemet or mirapex, although have prescriptions
for both.
Considering the bad side effects of Mirapex, sinemet,
or Requip, CoQ10 is a lot better. Practically no side effect, not even
the sudden "off feeling" if you forget a dose. Since this being a natural
compound our body makes anyway, this does not have virtually any side effect
upto 300 mg/day or so. But, one should take vitE or eat about 20 almonds
(rich in Vit E) along with CoQ10 to make it absorbable better. Also I take
it along wth my food.
That is my story!
brightline
**************
----- Original Message -----
From: "Linda J Herman" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Monday, November 04, 2002 8:24 PM
Subject: Re: CoQ10 Study Results
> I have a copy of the full CoEQ10 article from the Archives of Neurology.
> It is in .pdf format and includes all the statistics and graphs. Will be
> glad to email it to list members who can understand the statistics and
> explain it to the rest of us.
>
> I'm finding that this study is causing a dilemma. The results - even if
> they are based on a small number of subjects did report that at the
> largest dose -1200 mg/ day there was clinical evidence of slower
> progression. Similar positive results were found in a study with
> Huntingon's patients, but with 600 mg/day.
> The researchers and the NINDS do not advise patients to start taking the
> substance based on this one study. Yet some of our neuros are telling us
> that we should -if there's a chance it will slow the progression and
> there were no reported bad side effects - why not?
>
> But if you buy the Vitaline product - used in the clinical trial and
> supposedly "proven effective" as stated by Vitaline- the "discounted"
> monthly cost for 1200 mg/day is about $200 a month. Because CoEQ10 is
> considered a food supplement , not a prescribed drug - it is not covered
> by medical insurance . How many people will be able to afford it?
> You can find web stores that sell it for about $100/month , but because
> it is not regulated by the FDA - you can't be sure of what you're
> getting. Some reports comparing different brands of CoQ10 report on
> variations from 17% - 100% of the active product.
>
> Would also welcome more thoughts / ideas on this.
>
> Linda
>
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