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Donald Thanks for you detailed reply, my Neuro has recommended that I take the Entacapone in conjunction with all my other meds. I will keep you informed as to the results. Nigel 48 dx 35 ----- Original Message ----- From: "Donald Diswinka" <[log in to unmask]> To: <[log in to unmask]> Sent: Friday, November 29, 2002 8:33 PM Subject: Re: Entacapone > Nigel > > I am not a doctor but ??Dyskinesias is usually from drug overdosing and > are seperate from tremors. Amantadine is what is used to control > dyskinesias--I have used Entacapone(Comtan) here for over a year now. > Entacapone has Extended Sinemet without increasing it's dosage on > times for me an extra 45-90 minutes depending mostly on stress > encountered during that time. My Sinemet 50/200 was wearing off in 3 > hrs 20 minutes average time. Now that same dose with Entacapone lasts 4 > hrs +. I am not sure from your description of meds that while it works > in my case and is an excellent compliment with Sinemet, I have no > experience using it with any of the drugs you listed, therefore cannot > say if it will help your Madopar. No side effects encountered > whatsoever from iEntacapone. > > Note: " Selegiline(eldepryl). Its main use is as an addition to > treatment with levodopa, particularly for people who experience > fluctuations in their mobility through the day. However over the past > few years Selegiline, has shown that it may have a detrimental effect > on the action of the heart." A study is being done to review its > affects. Eldepryl belongs to a class of drugs known as MAO inhibitors. > Amitriptyline- is contraindicated with any MAO inhibiters. " It should > not be given concomitantly with a MAO inhibiting compound." > > Your Cabaser--A dopamine agonist is what is supposed to help Madopar be > smooth throughout its cycle. I am wondering if the neuro gives you > Entacapone what will he do with Cabaser and or Selegiline which are > all designed to do the same " smooth out" but with a different method? > > Don > 54/5 > > > On Friday, November 29, 2002, at 02:18 AM, nigel harland wrote: > > > Hello all, > > After several years of a reasonably managed medication > > regime, the dreaded dyskenesia is making a slow but definite comeback. > > I mentioned this to my Neuro this week, and he recommended that I > > include Entacapone into my regime. Has anyone any experience of > > Entacapone, good or bad, which they could share with me?? > > My present meds are Madopar dispersible (187.5mg) 4 times a day, > > Cabaser 4mg once a day, Amantadine 200mg once a day, Eldepryl 10mg > > once a day, and finally Amitriptyline 50mg once a day. > > > > Thanks, > > Nigel age 48, dx aged 35 > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn