 |
 |
Dear RAYILYN, and PIEN friends, Have you tried taking Sinemet 30 minutes before eating? It won't work as well if too much food , especiallly protein- rich or fatty foods block it from being absorbed. If you took Sinemet when you sit down to eat, it will work POORL Y and UNPREDICTABLY. Both SInemet CR and Sinemet contain L-dopa, or levo dyhydroxy phenylalanine. Phenylalanine is a long-chain amino acid, and a building block of larger protein molecules. Rayilyn,if YOUR DIET is too high in protein, the semi-permeable blood-brain barrier will not allow your brain to absorb the L-dopa in either Sinemet or in Sinemet CR . Your diet, if it is a typical American diet, is protein-rich. Noraml eating will supply the brain with so many amino acids that the blood-brtain barrier's "gates" will be closed by the time the L-dopa from the Sinemet tries to get through. Both Sinemets are designed to disperse their L-dopa in the blood stream, which then heads for the brain, only after their L-dopa achieves absorption in the INTESTINES. I wish that the pharmaceutical companies would make up a new L-dopa - containing medicine, that is fast-acting, and absorbed UNIFORMLY in the mouth, nose, throat or at least, stomach. The waiiting time for Sinemet is truly shameful. Ivan Suzman Mailbag Editor,. PDF 53/39/35 way too long. On Sun, 9 Mar 2003 17:09:44 EST Rayilyn Brown <[log in to unmask]> writes: > Hi, Sharon,, > > my tremors and dystonia were never helped by PD meds' n fact after > a year on > Sinemet (I was "ON" for a couple of hours), my foot/toes dystonia > got worse. > so I don't take PD meds now - my 7th year. Botox injections in my > leg didn't > help either. > > I have the awful stiffness now and use an electric wheelchaiir > part-time - > exercise in my exercise-therapy pool and am hoping to drag ny body > back to > treadmill again. A year ago I could do a mile on it. I am just > "OFF" all the > time, but meds were woefully inadequate. My first neuro told me PD > meds were > "tricky" - now I know what he meant. > > It seems I am in a minority - most people on the List benefit > greatly from > the meds and yes, I have a F-DOPA PET scan from UCLA that confirms > diagnosis > of idiopathic PD by 5 neuros. > > Hope you have better luck than I have, but if you don't, you are not > alone. > > Rayilyn - 60/67 > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn