Hi, Sharon,, my tremors and dystonia were never helped by PD meds' n fact after a year on Sinemet (I was "ON" for a couple of hours), my foot/toes dystonia got worse. so I don't take PD meds now - my 7th year. Botox injections in my leg didn't help either. I have the awful stiffness now and use an electric wheelchaiir part-time - exercise in my exercise-therapy pool and am hoping to drag ny body back to treadmill again. A year ago I could do a mile on it. I am just "OFF" all the time, but meds were woefully inadequate. My first neuro told me PD meds were "tricky" - now I know what he meant. It seems I am in a minority - most people on the List benefit greatly from the meds and yes, I have a F-DOPA PET scan from UCLA that confirms diagnosis of idiopathic PD by 5 neuros. Hope you have better luck than I have, but if you don't, you are not alone. Rayilyn - 60/67 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn