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initiation, speed, tremor, and tone.

This clinical trial will be limited to patients who experience
disruptive slowness of movement or difficulty initiating movements (also

known as "freezing" or start hesitation).   In addition, participants
must be over age 20 (male or female), have a diagnosis of mild to
moderately severe PD (Hoehn and Yahr stage II-IV), be on a stable
regimen of antiparkinsonian medications, and not experience disabling
memory impairment.   Subjects with a pacemaker or brain-stimulating
device are not eligible for the study.

The study will take place at Johns Hopkins Hospital and will require
about 4 hours of testing.  The testing can take place over two separate
days.  Participants will be provided free parking and compensated $20
for their time and the costs of traveling to Johns Hopkins.  If you are
interested in participating, please contact Melissa Gerstenhaber, R.N.,
M.S.N., Research Nurse Coordinator for the Morris K. Udall Parkinson's
Disease Research Center of Excellence at Johns Hopkins (410-614-1242) or

email her at [log in to unmask]  The principal investigator of this
study is Laura Marsh, M.D..  Lockheed Martin Corporation and the
National Institutes of Health are providing financial support for the
study.

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Note: If you are interested in participating in the study or have
questions related to participation, contact Melissa. Otherwise, please
do not contact her with technical questions about the device works.

You can address technical questions to me.

Phil Gesotti 53/dx46

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