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My 2 cents: Comtan is not an agonist--it's a COMT inhibitor--it more or less potentiates, maximized Sinemet--more of it gets to the brain. Charlotte Mancuso Winnie Carolgray <[log in to unmask]> wrote:I take comtan and permax. WINNIE CAROL GRAY ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn In the body of the message put: signoff parkinsn