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Date sent: Sun, 30 Mar 2003 12:55:15 -0500 Send reply to: Parkinson's Information Exchange Network <[log in to unmask]> From: janet paterson <[log in to unmask]> Subject: PMID: 12640080: Surgery for PD: no reliable evidence To: [log in to unmask] > Surgery for Parkinson's disease: lack of reliable clinical trial > evidence. > > There has been a striking resurgence of interest in surgery for > Parkinson's disease (PD) with new targets identified and new > procedures developed. This systematic review identified over 500 > studies of surgery for PD published since 1990, including over 10,000 > patients. However, the authors were unable to assess the value of PD > surgery reliably because only seven randomised trials were identified > including just 196 patients. Studies of surgery for PD have generally > been of poor quality with too few patients, too short follow up, > inappropriate choice of outcome measures, and lack of control groups. > Much larger, randomised, controlled trials are needed to assess the > longer term effects of surgery on patient rated quality of life and > cost effectiveness. > > J Neurol Neurosurg Psychiatry 2003 Apr;74(4):519-21 > Stowe RL, Wheatley K, Clarke CE, et al. > University of Birmingham, Birmingham, UK > PMID: 12640080 > I generally agree with this article. Best, Bob ********************************************** Robert A. Fink, M. D., F.A.C.S., P. C. 2500 Milvia Street Suite 222 Berkeley, California 94704-2636 Telephone: 510-849-2555 FAX: 510-849-2557 WWW: http://www.rafink.com/ mailto:[log in to unmask] "Ex Tristitia Virtus" ********************************************* ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn