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Hi all, I just read an ad in our local newspaper advertising a new research study being run at Duke University, testing a new drug for Parkinson's. The website for this research study is: www.pdstudy.com. Below is a description of the study and the drug they are testing. It is a national study, and is being conducted at many sites around the country. Have any of you heard of this study, or this drug? I'm considering volunteering for it, but I don't want to do anything that will exacerbate my PD symptoms. Just wondering if anyone is familiar with this study. Any input would be appreciated. PRECEPT STUDY: Physician Information The following information on this study for physicians can be printed out and given to your primary care doctor or neurologist. Clinical Research Study Inclusion-Exclusion Criteria for Physicians The PRECEPT Study is a randomized, double-blind, placebo-controlled, dose-finding study to assess the efficacy and safety of CEP-1347 in patients with early Parkinson's disease. CEP-1347 is a potent inhibitor of members of the mixed lineage kinase (MLK) family. MLK family members are key participants in the activation of c-Jun N-terminal kinase (JNK), which is thought to underlie neuronal dysfunction and subsequent death. Research at Cephalon and H. Lundbeck A/S has shown that CEP-1347 enhances the survival of neurons that produce dopamine. Additionally, animal models of Parkinson's disease have shown that CEP-1347 protects the dopamine-producing neurons in the specific area of the brain affected by Parkinson's disease. The primary objective is to determine if treatment with CEP-1347 delays the time to onset of disability sufficient to require dopaminergic therapy. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn