After trying 5 different PD meds, I did some research and decided to try Benedrly. I've only been taking two 25 mg per day (to get me through the work day). It does seem to help my tremor and the curling of my middle toe on the affected side. I take it a 7 a.m. and 1 p.m. I get very sleepy in the afternoon. Benedryl has some anticholinergic effects and was the usual course of treatment before these fancy drugs came out. Be careful mixing it with other PD drugs, especially anticholinergics. Roberta ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn