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Hi Bob I am 47 years old and I was diagnosed a year ago in April. I decided to see a Neurologist when I was having anxiety problems. I am currently taking Sinement and also taking Requip. My main problems are the termors in my right leg and foot, which it makes it difficult to drive at times. I am still experimenting with my dosages of medication to control my PD. I am a Quality Engineer for an Automotive supplier and I deal with a lot of stress and travel. If not for the medications, I would not be able to function in my job adequately. The Requip along with the Sinement help me immensely, but the Requip has a tendency to make me very drowsy. You need to experiment to find the right intervals and dosages that work for you. Also I find that taking vitamins B-100 Complex, B-12, C, E, and a multi vitamin without iron, helps me with my fatigue. I feel that you should consult your Neurologist and find what works for you. Good Luck, Keith ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn