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Hi Sharon I am taking 5 tablets of 25/100 Sinemet daily and 3 doses of Requip daily. The side effects of the sinement makes me walk funny so I take a half tablet about every two hours or so during the day. I take a whole tablet in the morning, and just before I go to bed. The Requip I take three times daily. one in the morning, oone at noon and one in the evening. The thing about Requip is that it makes me drowsy, sometimes I have a hard time keeping my eyes open, especially at work. It's not so bad if you can keep moving to ward off the drowsiness. This usually lasts about two hours after I take my dose. I don't like taking it before I have to drive any distance. Falling asleep behind the wheel could be bad. I also went to physical therapy and learned to exercise my right foot and arm. I exercise these limbs for about a half an hour a day. I believe this along with the medication helps. I just want to let you know, I do have my bad days that it seems that nothing seems to control the tremmors to my satisfaction, but I seem to have more good days than I used to. You need to find the right dosage and intervals that work for you. PD effects each individual differently. What works for one dosen't mean that it will work for you. As I progress I feel I will have to find the right combination of medications and exercise all over again to control my symptoms. Good Luck, Keith ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn