Ellyn, I experience shortness of breath as part of my "On-Off" cycle. I noticed it happening some time after I switched from 25/100 Carbidopa-Levodopa imediate release to 50/200 Carbidopa-Levodopa ER (extended release) enhanced with 200 mg Comtan. The shortness of breath happens as my last dose wears off or as my new dose ramps up. If I take my next dose as soon as I detect the end-of-dose feelings, I avoid some of the breathing issues and other symptoms - but at the risk of shortening my cycle. My schedule is four doses a day at four hour intervals. Some of the things I do to stretch out a dose include relaxing rituals (stretching, Yoga, Tai-Chi) and being very careful about the quantity of protein I eat and when I eat it. Best of luck on your journey, Geo. Ellyn Berman <[log in to unmask]> Sent by: Parkinson's Information Exchange Network <[log in to unmask]> 07/04/2003 07:36 PM Please respond to Parkinson's Information Exchange Network To: [log in to unmask] cc: Subject: Re: What works? (For Sharon) Does anyone suffer from shortness of breath? Is it related to Parkinson's? My husband who was diagnosed a couple of years ago and is on Sinemet is experiencing this symptom. Please let me know. Thanks, Ellyn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn