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Kathleen, I don't wish to be rude but I really wonder whether you and other members of PIEN have read any of my postings because I pointed out a number of times that 'Prothiaden' (Tricyclic antidepressant) induces Parkinsons; is documented as such by the BMA (UK equivalent of AMA) and has been withdrawn. I was taking this from 8/88 thru 1/90; by the end of 1990 the first PD symptoms appeared. I am fed up with trying to motivate this group into setting up a database to see how many have taken any form of anti-depressants in the past especially YOP's. I firmly believe that anti-d's and perhaps illegal drugs (heroin, cocaine, hash, etc.) are the cause of the initial damage; which is then compounded with drugs like Sinemet. I ask you and all those on the list this simple question, if you are taking Sinemet or Similar; how soon after initial diagnosis did you start taking Sinemet and initial dosage, how many times was the dosage increased and why, and what is the present dosage. How were you physically at the beginning and now; better or worse. I'm not an Academic or have any indepth medical knowledge but God has blessed me with intelligence and an enquiring mind, and a spirit of determination to find the cause(s) of PD and start the process of treating the cause(s) and not the symptoms. Taking ever increasing amounts of synthesised dopamine is in my opinion 'the nail in the coffin'. Why? Because it is impossible to measure how much is being produced naturally, the sum of this plus tablet form (taken at intervals we decide rather than when the brain/body requires it) almost always creates an excess amount, therefore, the brain produces less and less and in time zero. And then as we all know the benefit of the meds end as well. Then we are left with DBS. All the current focus on stemcells is a waste of time because it is not connected to any specific cause. And is more dangerous than sinemet because they are living cells, from another body and no one knows how much to give each case. Look at the results of the first trial (in NY, I think) which went very wrong. It's 10yrs since I was diagnosed; I didn't take any meds until 2/99, when I started with Pergolide(permax) and in 8/02 started Sinemet. I keep the dosage at a minimum: 2 x 1mg Pergolide and 3 x 62,5 Sinemet per day. Other than occasional problem with walking and swollen ankles I'm AOK. Both the diagnosis and drug therapies are outdated. I don't really believe any organisation is really looking into cause(s). All R&D is on treatment of symptoms. Why? because the resulting therapies generate an ongoing, significant, revenue stream for the Pharmaceutical Co.'s. I read somewhere recently that when one medical student told a colleague he was going to specialise in Neurology, the colleague replied, " why bother because it's 'diagnose and adios'". That's pretty sad, don't you think. Makes me wonder if we're just human lab-rats! I'm sorry if I've gone on a bit but I feel passionately about this. Kind regards, Marco (54/M/93, London, England) ----- Original Message ----- From: "Kathleen Cochran" <[log in to unmask]> To: <[log in to unmask]> Sent: Saturday, July 26, 2003 1:11 PM Subject: Re: ARTICLE: Can Some Parkinson's Drugs Cause Alzheimer's-like Symptoms? > In a message dated 7/26/03 2:21:02 AM, [log in to unmask] writes: > > << The drugs that block acetylcholine receptors in Parkinson's patients are > called "antimuscarinic" agents and are usually > prescribed to control tremors and bladder dysfunction. Tricyclic > antidepressants have the same effects and are also > sometimes prescribed for these individuals. >> > > This is scary stuff. Does anyone know the names under which these drugs are > sold? > > Kathleen > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn