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On 13 Sep 2003 at 14:19, larraf wrote: can someone please advise what is the maximum number of mg. of carbidopa and levadopa that an individual can safely take within a 24 hour period and the source of your information..... by "safely take", i am not referring to negative effects of the medicine which can cause adverse pd symptoms.... i am referring to toxic effects on body organs such as liver, kidneys, etc. thanks.. ---------------------------------------------------------------------- Hi, This web site has dosage info.... Sinemet Dosage http://www.pharmacynetworkgroup.com/i/sinemet-indications-dosage.htm my personal opinion is that the optimum quality of life is obtained by being just slightly under dosed... requires very careful titration up 'n down... over dosing is not desirable.... cheers ...... murray * * * Murray Charters <[log in to unmask]> Parkinson's Resources on the WWWeb http://www.geocities.com/murraycharters/ ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn