--- "Nancy S. deGrazia" <[log in to unmask]> wrote: > Thank you, Chris : > No. my "end of dose " phenomenom is the onset of > dyskinesia. I seem to > have both "peak dose" and "end of dose" dyskinesia. > I have been taking > sinemet for almost 10 years and over that period > have added eldepryl, > permax, mirapex and amantadine. I guess the reason I > am taking so many > different things is that I am hypersensitive to > levadopa. I take 1/4 of > a 25/100 every 90 minutes and if I take more the > dyskinesia is just awful.. > > Anyone else with this kind of problem? > I used to have diskinesias that on a 1 to 10 scale mine were up to 13 or 14 . Then i had a pallidototomy. For the most part I have been free of dyskinesia since then (1995} David Moreland > Nancy deG > > Chris Lui wrote: > > >Hi Nancy: > > > >My end of dose phenomenon refers to premature > ending of the effectiveness of > >the medicine, a shortened drug effect experienced > after 3 years of > >medication. Have you got the similar problem? > > > >Chris Lui > > > >----- Original Message ----- > >From: "Nancy S. deGrazia" <[log in to unmask]> > >To: <[log in to unmask]> > >Sent: Tuesday, September 16, 2003 6:57 PM > >Subject: Re: COMTAN > > > > > > > > > >>Chris Lui:- iis the "end of dose" phenomenon you > referred to (A) a > >>premature ending of the effectiveness of the > medecine or (b) dyskinesia > >>which manifests itself at the end of a dose? > >> > >>Your response will clarify my situation for which > I would be very > >> > >> > >grateful. > > > > > >>Nancy S deGrazia > >> > >> > >> > >>Chris Lui wrote: > >> > >> > >> > >>>Hi ALL, > >>> > >>>Today my neuro starts putting me on COMTAN to > addrerss the end of dose > >>> > >>> > >phenomenon. Any one has got any advice or comment > about the use of this > >drug? Be it favourable or adverse, your > experience would certainly help! > >Thanks! > > > > > >>>Chris Lui > >>> > >>>---------------------------------------------------------------------- > >>>To sign-off Parkinsn send a message to: > >>> > >>> > >mailto:[log in to unmask] > > > > > >>>In the body of the message put: signoff parkinsn > >>> > >>> > >>> > >>> > >>> > >>---------------------------------------------------------------------- > >>To sign-off Parkinsn send a message to: > >> > >> > >mailto:[log in to unmask] > > > > > >>In the body of the message put: signoff parkinsn > >> > >> > >> > > > >---------------------------------------------------------------------- > >To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > >In the body of the message put: signoff parkinsn > > > > > > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn