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US Govt. Funds Controversial Stem Cell Work
Monday, September 29, 2003 Posted: 4:46 PM EDT (2046 GMT)

WASHINGTON (Reuters) -- Saying the research offers huge potential, the U.S. government announced three small grants on
Monday for researchers to examine human embryonic stem cells.

Work using the cells is controversial because opponents say it is unethical to work on human embryos, however tiny.
President George W. Bush agrees and has strictly limited federal funding for the work to batches of cells that existed
as of August 2001.

The National Institutes of Health announced it was giving $6.3 million over three years to three centers to work on
their stem cells -- the University of Wisconsin's WiCell Institute; the University of Washington Seattle and the
associated Fred Hutchinson Cancer Research Center; and the University of Michigan Medical School.

"America's scientists need powerful tools to find better ways to diagnose and treat health problems," Health and Human
Services Secretary Tommy Thompson said in a statement.

"Understanding the biology of stem cells can help fill in the blanks about what causes cells to misbehave in disease."

Stem cells taken from tiny embryos just a few days old have the potential to form any kind of cell, tissue or organ in
the body.

Scientists hope to learn how to direct their development, with the eventual aim of personally tailored treatment for
patients with a range of diseases from juvenile diabetes to Parkinson's. The cells could also treat spinal cord
injuries, cancer and heart disease.

Several types of stem cells can be used, but researchers believe embryonic stem cells are the most flexible. Now they
must be made using cloning technology, but the hope is that by studying embryonic stem cells, scientists can figure out
how to take any old cell and make it perform the same magic.

"What gives stem cells their unique property to self-renew? When, how and why does a stem cell decide to differentiate,
becoming another kind of cell?" NIH director Dr. Elias Zerhouni asked in a statement.

"There is so much basic research we must conduct before we can unlock the potential of these cells and fulfill their
promise," he added.

Supporters of stem cell research say federal funding is vital to keep the work in the public domain and make sure that
ethical constraints are followed.

The researchers receiving the grants include the University of Wisconsin's James Thomson, one of the discoverers of
human embryonic stem cells.

SOURCE: Reuters / CNN
http://www.cnn.com/2003/HEALTH/09/29/government.cells.reut/

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