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Limits on funding of stem cell research is discouraging young scientists, experts say. WASHINGTON, Oct 02, 2003 (AP WorldStream via COMTEX) -- The U.S. government's policy of restricting federal money for embryonic stem cell research may be discouraging young scientists from pursuing such work despite its great promise, researchers said Thursday. "I am sure that the narrow scope of the research is making young investigators wary of entering a field who future is uncertain," Dr. Harold Varmus, a former head of the National Institutes of Health, told a joint House-Senate hearing. Varmus, NIH Director Elias Zerhouni and former Princeton University President Harold Shapiro were called to testify about Zerhouni's plan to reshape the research structure at NIH. Although there was praise for Zerhouni's plan, most lawmakers quickly moved to other topics, including stem cell research, shifting NIH jobs to the private sector and federally funded sex research. Rep. Henry Waxman quizzed Zerhouni about the effect of the Bush administration's policy to forbid federal funding of embryonic stem cell research except for cell colonies developed before August 2001. This limitation "could have a chilling effect on research. A researcher won't want to be in a situation where they might be gagged," Waxman said. Zerhouni said there are now 12 federally approved cell lines, or colonies, available for research and that "the number of cells lines is not the immediate problem." More pressing, he said, is the scarcity of scientists who have the specialized training needed to work with the complex embryonic stem cells. "We need more people who understand the cellular pathways," Zerhouni said. Varmus, now president of Memorial Sloan-Kettering Cancer Center in New York, said he was happy that "the door is at least partially open" for federal dollars. But, he added, much of these studies eventually will have to be undertaken by private institutions such as his own. "I personally regret the idea we'll have to have a segment of medical research conducted without federal funds," the Nobel laureate said. Zerhouni said the administration's position on embryonic stem cells "is based on moral and ethical considerations." Embryonic stem cells, which form within a few days of conception, are the ancestral cells for all the tissues in the body. Many scientists believe these cells can be coaxed in the laboratory to transform into liver, heart and other cells for use in renewing ailing organs. Many oppose research with human embryonic stem cells because isolating the cells requires the death of a human embryo. Regulations that President George W. Bush issued in 2001 were intended to prevent the killing of more human embryos for research purposes. Also during the hearing of the Senate Health, Education, Labor and Pension and the House Energy and Commerce committees, Rep. Joseph R. Pitts took issue with some NIH grants, costing more than $15 million over six years, that pay for research into human sexuality and arousal. "One grant pays people to watch pornography and drink alcohol before watching pornography," said Pitts. Other grants pay for studies of California prostitutes, the sexual habits of older men and sexual arousal among gays and lesbians, he said. Zerhouni, who noted that he was not an expert in this field, said advisory committees had review each grant and approved them based on scientific value. Last July, the House narrowly defeated an attempt by Pitts and others to block funds for the sexuality research grants. --- On the Net: National Institutes of Health: http://www.nih.gov By PAUL RECER AP Science Writer SOURCE: Associated Press / MacroWorld Investor http://www.mworld.com/m/m.w?lp=GetStory&id=74508121 * * * ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn