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Judith, PD meds don't seem to help me either. I've just had bilateral DBS brain surgery in subthalmus nucleus and it really helps tremor, but other things are atypically worse, like walking and speaking I don't have DRD (Dopamine Responsive Dystonia)(DBS is now done on the globus pallidus "sp"?for dystonia) and was only "ON" the first time I took Sinemet. Told my neuro I have never gotten the "Big Bang" out of meds like most people do. she conceded I was a "weird duck", but believes I do have PD as I have every syjmptom except facial mask and and PET scan which supports the diagnosis of idiopathic PD. Am going for another programming hopefully next week. She even asked me what I thought I had. It is very discouraging. Ray ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn