Print

Print


Edinburgh to lead landmark European Initiative in Stem Cell Research
HERO ref: 24266 Tuesday 03 February 2004

University of Edinburgh
Scientists from throughout Europe will meet in Edinburgh this week for the launch of an EU-funded research project that
will establish foundations for future clinical trials of stem cell therapies. The four-year project involves 14
organisations from eight European countries and will be coordinated from the Institute for Stem Cell Research in
Edinburgh.

Stem cells may hold the key to replacing damaged tissue in devastating diseases such as Parkinson's and muscular
dystrophies, but more basic information about stem cells is required before they can be tested in the clinic.
EuroStemCell is a trans-European research effort to obtain this knowledge for different types of stem cell and
investigate their potential for treating degenerative diseases.

The breadth and scale of the EuroStemCell project are unprecedented in the field of stem cell research. For the first
time, an integrated team of world-class scientists will compare the basic properties of stem cells from embryonic,
foetal and adult tissues and in parallel will evaluate their therapeutic prospects. The project also aims to promote
the development of a European stem cell bio-industry that can compete effectively with North America and Japan.

Key scientists taking part in EuroStemCell will be meeting in Edinburgh this week for the launch of the project.
Professor Austin Smith, Director of the Institute for Stem Cell Research, University of Edinburgh, who has the task of
co-ordinating EuroStemCell says "After all the hype, now is the time to find out whether we can understand stem cells
well enough to use them for medical benefit. The EuroStemCell project is very exciting because it unites the very best
European stem cell researchers in this challenge. Our common goal is to advance this research from the laboratory
towards the clinic."

Professor Anders Bjorklund, Lund University, Sweden, who has pioneered research into stem cell transplantation therapy
for Parkinson's disease, is Deputy Coordinator of EuroStemCell. He said: "We have seen some real benefits in some, but
not all, Parkinson's patients who have undergone cell transplantation therapy. We are convinced the benefits and safety
of such treatments can be improved by using properly defined stem cells."

EuroStemCell is funded through the European Commission Sixth Framework Programme and more specifically the priority on
Life Sciences, Genomics, and Biotechnology for Health, which aims to advance medicine and quality of life for European
citizens. The Commission is providing 11.9 million Euro support to the EuroStemCell Project during its four year
duration. The 14 participants are from Scotland, England, Sweden, France, Denmark, Italy, Germany, and Switzerland.
They comprise universities, research institutes and 3 biotechnology companies. The project was selected after a call
for proposals and very positive evaluation by independent experts.

Important Note: The EuroStemCell project includes work on mouse embryonic stem cells and tissue stem cells of mouse and
human origin. Research on human embryonic stem cells is not included in the current project.

Glossary of stem cells:
Stem Cell - unspecialized cell that has the ability to divide for indefinite periods of time, and can also give rise to
specialized cell types in the body.

Embryonic stem cell - Stem cells originating from the early embryo that have the potential to make most cell types both
in the body and in the laboratory

Adult stem cell - Tissue stem cells taken from adults (i.e. bone marrow, skin, muscle etc.). Tissue stem cells are
undifferentiated cells found in a specialized tissue. They have the ability to make a limited range of specialised cell
types.

Foetal Stem Cell - Tissue stem cells originating from the foetus that have the potential to make a limited range of
specialised cell types.

Regenerative medicine - It is hoped that stem cells will be able to replace/replenish tissue that has been diseased or
damaged. For example, in Parkinson's disease for which there is no effective current cure, it is hoped that stem cells
will be able to replenish the damaged nerve cells.

(11,900,000.00 Euro = 14,931,898.34 United States Dollars ... roughly $15 million... murray)

SOURCE: HERO Higher Education Research Opportunities
(HERO is the official gateway site to the UK's universities, colleges and research organisations)
http://www.hero.ac.uk/media_relations/5823.cfm

Reference:

EuroStemCell ... Opportunities in Stem Cell Research
http://www.eurostemcell.org/

What is FP6?
http://www.cordis.lu/fp6/whatisfp6.htm

Key word -  neuroscience ... 38 Expressions of Interest
http://tinyurl.com/3ds62

Expressions of Intterest (EoI) for Integrated Projects (IP)
http://cellnet.org/001_network/eu/list.htm

Bioethics Today UK
http://www.bioethics-today.org

Bioethics Today UK Sitemap (scroll top to bottom .. bookmark?)
http://www.shef.ac.uk/b/bioethics-today/FSsitemap.htm

Archives of News Items on Parkinson's (2004)
http://www.shef.ac.uk/b/bioethics-today/archives/files/Parkinsons2004main.htm

HERO home page
http://www.hero.ac.uk/index.cfm

HERO Sitemap
http://www.hero.ac.uk/sitemap.cfm

* * *

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn