 |
 |
STUDY: Clozapine Controls Levodopa-Induced Dyskinesia (LID). In patients with severe PD, low-dose clozapine, an antipsychotic drug, reduced involuntary movements by around 50%. (Friday, 26 March 2004) At five hospitals in France, 50 patients with severe PD participated in the 10-week clinical trial. Neither patients, nor research staff knew which participants (25) received the experimental treatment (clozapine, 39,4 mg on average) or placebo once-daily (25). The maximal LID score at rest was significantly decreased under clozapine treatment. Three patients in the clozapine group developed reversible eosinophilia. Durif F et al - Neurology - 2004; 62: 381-8. SOURCE: World Parkinson's Disease Assoc. (WPDA) News http://www.wpda.org/news.html?n=703&m=-1&y=0 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn