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When I first went to my neurologist I was on Effexor.  He told me that Effexor causes tremors.  I had the termors before I took Effexor but went off it to see what the effect was and I still had the tremors.

Greg Louis <[log in to unmask]> wrote:On 20040417 (Sat) at 0941:27 -0500, Lynn Maruska wrote:
> Any experiences with taking Wellbutrin for depression and experiencing PD
> symptoms? Doctors have discounted the connection because symptoms are
> unilateral but ..... I had noticed when I'd increase my dosage of
> Wellbutrin my PD symptoms increased. Recently had to stay off Wellbutrin
> for a couple of days because of stomach flu. All PD symptoms reduced and
> even seemed to be gone. Dr. put me on lower dosage of Wellbutrin with
> extended release. Within a day symptoms returned. I also take low dosage
> of Effexor. All symptoms on left side. Had shingles a few years ago also
> on left side. Perhaps Wellbutrin exasperates PD symptoms.

Sounds familiar, except in my case it's the right side and the symptoms
appeared for the first time when I tried Effexor last July. They
seemed to get milder after I stopped taking Effexor, but unfortunately,
they didn't go away (and seem to be slowly worsening month by month
since then). I don't think Effexor was a cause, but perhaps it acted
as a trigger.

Since the chemistry of both PD and most antidepressants is understood
only at a fairly superficial level, there could be some as yet unknown
relation. Most doctors work empirically; they can hardly do otherwise,
since it would be more than a full-time job just staying current in all
the fields a GP needs to know about. Even specialists tend to read
review literature rather than original science. Having to make
life-and-death decisions on insufficient evidence (even when the
reading is done, science itself can be incomplete or plain wrong) tends
to make some physicians appear dogmatic; I think it's a kind of
psychological defense against fundamental insecurity. I don't mean
that as a criticism, either: medicine is a hard job, and that's one of
the factors that make it so.

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