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Exciting news... this is a non controversial source of stem cells that
deserves some attention.  It sounds promising but then all discoveries sound
promising at some stage.  The most important thing about this is that, in
principal, research done in this area should not be opposed by many who are
currently opposed to human cloning and the use of embryos in research.

Now if only we could channel some of the efforts that go into advocating
controversial methods into support for those less controversial... Choose
your battles wisely.  This may be one where there is little resistance and
it leads to the same goal.  Others are assaults on more heavily defended
positions that may cost additional time and heavier casualties.

Frank cg. Teri 52/47/40 15024



----- Original Message -----
From: "Murray Charters" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, May 04, 2004 10:41 AM
Subject: Blood Cells Can Become Brain Cells


> Blood Cells Can Become Brain Cells
> May 4, 2004 - Tehran Times
>
> WASHINGTON (Health Day News) -- It appears that after a bone marrow
transplant, some of the transplanted blood stem
> cells can become brain cells, researchers report.
>
> This finding suggests a patient's own bone marrow might be used as a
source of stem cells to regenerate lost nerve
> cells.
>
> Stem cells are cells that have not yet become a specific type of cell; the
potential exists for them to become any kind
> of body cell.
>
> If a way can be perfected to deliver these cells directly to the brain,
transplanted blood stem cells might provide
> treatments for neurodegenerative diseases and traumatic brain injury.
"Blood can make brain," said lead researcher Dr.
> Christopher R. Cogle, a postdoctoral associate from the University of
Florida. "The brain is not a static organ. It
> does have some regenerative capacity."
>
> "We wanted to see if the transplanted bone marrow cells contributed to the
production of new neurons," said co-
> researcher Dr. Eric D. Laywell, an associate professor of anatomy and cell
biology at the University of Florida.
>
> The research team looked at brain tissue from three women who had received
bone marrow from male relatives to help
> treat leukemia. They found male Y chromosomes in the brain tissue of all
three women.
>
> But the woman who survived the longest had three different types of male
brain cells, including microglia, neurons and
> astrocytes.
>
> "In this woman, we found neurons that had both X and Y chromosomes, which
means that they came from the transplanted
> male bone marrow," Laywell said.
>
> The male neurons made up 1 percent of the neurons in her hippocampus,
according to the report in the May 1 issue of The
> Lancet.
>
> "It appears that adult blood stem cells have the capacity to make other
cell types," Cogle said. He noted these new
> cells were not male stem cells that were fused to female cells, but were
newly created brain cells.
>
> "If it is possible for bone marrow to turn into nervous tissue, then
everybody is walking around with a potential
> replacement source of nervous system cells," Laywell said.
>
> The next step in the research is to try to find ways to make adult blood
stem cells repair the brain in a much more
> robust way. "We need to find what signals blood cells to go into the brain
and make brain cells," Cogle said.
>
> "Our findings imply that blood stem cells may be a source for repairing an
injured brain in patients with Alzheimer's
> or Parkinson's or brain trauma," he added.
>
> "Every time I spend time with my grandmother, who has a neurodegenerative
disease, all I can hope is that our center
> and other centers work as hard and as fast as we can to help find a cure,"
Cogle said.
>
> Dr. Neeta S. Roy, an assistant professor of neurology from Weill Medical
College of Cornell University, said this
> finding is "amazing." It is the first demonstration that confirms that
blood stem cells can become neurons, she added.
> However, "even though these cells look like neurons, it doesn't mean that
they are functioning neurons -- neurons that
> can actually do something, like heal brain damage," Roy cautioned
>
> SOURCE: Tehran Times
> http://www.tehrantimes.com/Description.asp?Da=5/4/2004&Cat=7&Num=5
>
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