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Ervin, I responded favorably to Sinemet only on my first half dose of 50/200 CR in 2000. I could walk to the mailbox and my body felt "normal", I took it for a year, but thereafter it never helped that I could tell. When I went to Scripps re DBS last year I had F-DOPA PET Scan from UCLA which said results were consistent with PD The DBS only helped my tremors, which were becoming bilateral, but for that alone it was worth it. My voice, ,altho it was getting bad off and on then, now is in really bad shape all the time. When my programmer turned me off over a month ago, my voice was immediately better. I also have double vision with letters and lights. Eye doc says my vision is OK. I read that double vision and voice problems were side effects of DBS. I have better upper body strength and can swim better (when I have the strength and motivation to do so), but sink now if I put my feet under exercise bar and with my legs try to bring my body to the bar. This was something I could do before DBS, but was getting so I couldn't "swim". Anyway, my neuerologist and I both agree I do have PD, but am a weird duck. Ray ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn