 |
 |
On 21 Jul 2004 at 11:11, Maxine Krugman wrote: > was wondering the same thing as dr fink...names mean very little > unless we can find out when and where published? thanks maxine >>2. Mucuna pruriens in Parkinson’s disease: A double-blind clinical and pharmacological study R Katzenschlager, A Evans, A Manson, PN Patsalos, N Ratnaraj, H Watt, L Timmermann, R Van de Giessen, AJ Lees P710, S249 Levodopa-containing seed powder from Mucuna pruriens (cowhage, velvet bean, atmagupta) produces a rapid-onset symptomatic treatment for Parkinson’s disease, according to this study. Eight patients with dyskinesias were randomized to receive either 200 mg levodopa or 15 or 30 mg M. pruriens followed by crossover. Onset of effect for the 30 mg dose was 34.6 minutes, vs. 68.5 minutes for levodopa (p = 0.021). Mean on time was 22% longer and area under the curve was 165% larger. No differences were seen in dyskinesias as assessed by two blinded video raters.<< This was re-posted and the article, although of some interest, is very limited in its scope. Only 8 patients were involved, and two "blinded" observers (blinded to who was getting what, of course!) saw no difference in 25% of the cases. Much more research will be necessary before Mucuna pruriens can be considered of value in Parkinson's disease. Best, Bob Robert A. Fink, M. D., F.A.C.S., P. C. Neurological Surgery 2500 Milvia Street Suite 222 Berkeley, CA 94704-2636 USA 510-849-2555 FAX: 510-849-2557 <http://www.rafink.com/> "Ex Tristitia Virtus" Disclaimer: That which is written in my e-mail is not to be considered as "medical advice". Such advice can only be given after a formal, in-person, consultation between doctor and patient. ********************************************** ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn