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EDITORIAL: End Of The Lines ... Stem Cells Between Promise and Handicap
Daytona Beach News-Journal, FL - Aug 2, 2004

Last update: 02 August 2004

Embryonic stem cells are harvested from week-old embryos. The embryos are
destroyed in the process. The cells, in theory, can be developed into any kind of cell
type in the human body, like interchangeable spare parts. In theory, the process
can lead to replacing diseased cells or body tissue with healthy replacements. In
theory, people coming down with all sorts of diseases, including Alzheimer's or
Parkinson's, could be cured.

The distance between theory and reality is untold years away, and indeed may
never be bridged. But scientists predict that time and a huge investment in research
will indeed bridge the distance -- for the same reason that Jules Verne could
imagine in 1865, and with striking accuracy, that men would one day reach the
moon "in 97 hours, 20 minutes": because vision drives discovery. So Ron Reagan
wasn't being fanciful when he told the Democratic National Convention last week
that stem cell research "may be the greatest medical breakthrough in our or any
lifetime."

For now, it is turning into one of medicine's greatest missed opportunities for the
wrong reasons: politics and ideology.

When President Bush explained his position on stem cell research in August 2001,
he reached for a strange compromise. He would allow research to continue on 60
stem cell lines already harvested from embryos, but would not allow federal money
to pay for research drawn from new stem cell lines. It was strange because the
compromise implicitly recognized the "unique potential" of stem cell research, thus
negating the argument that it's a medical fantasy. Noting that stem cells can also be
derived from adult cells, Bush also conceded that "most scientists, at least today,
believe that research on embryonic stem cells offers the most promise." Still, with
the religious right breathing down his electoral prospects, Bush agreed to the
strange compromise.

Without federal money -- that is, without the involvement of the National Institutes of
Health -- stem cell research is set back the way, say, a trip to the moon might be set
back without NASA's involvement. It's not entirely impossible. But the obstacles are
daunting. And while the president was right that existing stem cell lines "have the
ability to regenerate themselves indefinitely, creating ongoing opportunities for
research," he was -- all matters of ethics aside -- wrong on two important counts.
Within days of his speech, the journal Science corrected him on the number of stem
cell lines available to researchers. There were 34, not 60 (10 of them in the United
States, the rest of them in Sweden, Australia and Israel). By February this year, the
NIH was reporting to Congress that in the "best case scenario," only 23 lines will be
available for federally funded research. And nothing says that those lines will
remain fit for research. They can be corrupted.

This is a controversy that, scientifically speaking, has no merit. Religious
conservatives have created a link between abortion and stem cell research that just
doesn't exist. In his own speech Bush pointed out that stopping the harvesting of
stem cells from embryos won't mean that embryos won't continue to be donated to
science by couples whose in vitro fertilization produces more embryos than they
need. It is from those embryos, which are otherwise frozen or destroyed anyway,
that new stem cells could be harvested.

Other ideological opponents of stem cell research point to the uncertainty of
success compared with the sums of money that would be spent. The cost-benefit
argument sounds appealing, especially when its purveyors trot out such factoids as
a 30-year, $40 billion war on cancer that has yet to yield a clear victory. But
considering that as much money has been spent on cancer research in 30 years as
on the drug war in a single year, the argument ought to be about whether the nation
has had its priorities straight.

Reagan was right last Tuesday: "We have a chance to take a giant stride forward
for the good of all humanity" in the next election. (John Kerry, the Democratic
nominee for president, supports federally funded stem cell research.) "We can
choose between the future and the past, between reason and ignorance, between
true compassion and mere ideology."

SOURCE: Daytona Beach News-Journal, FL - Aug 2, 2004
http://tinyurl.com/579ut

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