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PRESS RELEASE: Shamrock Structures to Provide Proteomics Services for
Biopharmaceutical Company
Thursday August 5, 9:03 am ET

WOODRIDGE, Ill., Aug. 5 /PRNewswire/ -- Shamrock Structures of Woodridge, Ill.,
has signed an agreement with Intra-Cellular Therapies, Inc. (ITI), a New York City-
based biopharmaceutical company, to provide integrated structural proteomics
services.

Under the agreement, Shamrock Structures will perform structure-activity
relationship (SAR) co-crystallization, synchrotron data collection, and structure
determination of an Intra-Cellular Therapies protein target to which inhibitors are
bound. The agreement terms include an upfront fee and performance-based
milestone payments. Additional terms of the agreement remain undisclosed.

"We are very pleased to support Intra-Cellular Therapies' drug discovery efforts
through Shamrock Structures' X-ray crystallography services," said Steve Schiltz,
Shamrock's CEO.

"Three dimensional structure determination of protein-inhibitor complexes will
further our ability to develop potent and selective new drugs to treat depression,
schizophrenia, Alzheimer's and Parkinson's disease," said Sharon Mates, Ph.D.
founder, chairman, and CEO of Intra-Cellular Therapies, Inc. (ITI).

Intra-Cellular Therapies, Inc. (ITI) is a privately held biopharmaceutical company
developing novel drugs for depression, schizophrenia, Alzheimer's and Parkinson's
disease, and other disorders of the central nervous system. The company is
headquartered in the Audubon Biomedical Science & Technology Park in New York
City. ( http://www.intracellulartherapies.com )

Shamrock Structures, LLC, based in Woodridge, Ill. (
http://www.shamrockstructures.com ) is a privately held, structural proteomics
company that determines the three dimensional structures of proteins and protein
complexes. The company offers integrated proteomics services and efficient access
to X-ray synchrotron data collection, enabling pharmaceutical and biotechnology
clients to decrease the time required to advance from protein targets to novel drug
development.

Source: Shamrock Structures, LLC

SOURCE: Yahoo News (press release)
http://biz.yahoo.com/prnews/040805/cgth003_1.html

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