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I would like to know why only 15% of pwps benefit from DBS also what do the psycho cognitive tests determine? I am 56 diagnosed 7 years ago with left side rigidity, now lead a reasonable life with 7 doses of Stelavo (L dopa25/100 + comt ) plus pergolide (1mgX7). I am wondering if early dbs is possible and desirable to reduce the drug intake and thus save my heart form the effects of pergolide, Would some one please comment and give me the benefit of their experience. I feel I am deteriorating faster and feel this is my only route to survive until the "cure" Shekhar Manchester ,UK ----- Original Message ----- From: M.Schild<mailto:[log in to unmask]> To: [log in to unmask]<mailto:[log in to unmask]> Sent: 27 September 2004 07:44 Subject: Re: DBS for PD and Dystonia: Long term Results >> "Are there any studies that look at the benefits of having >> DBS before vs >> after levadopa treatment? Or is DBS only tried after levodopa no longer >> is effective?" > The short answer is no. DBS has only had wide spread use for about the > last 5 years. In fact, in France they have been performing DBS for about 10 years now. They started doing it mainly on advanced cases. Now the tendency is to do it on moderate cases and not after 70 years of age and never without extensive psycho/ cognitive tests. They reckon it can benefit about 15% of all PWPs Maryse cg JOhn 75,15 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask]<mailto:[log in to unmask]> In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn