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I've joined the list on behalf of my mother. I hope to get her online and an active participant soon. She has had Parkinsons for about 15 years, diagnosed when she was 47. At this stage, she still manages with optimism but things are getting difficult. In particular, I am interested in any information or ideas people have regarding coping with nights, or more generally with the need for constant assistance in taking medication due to the unpredictability of ons and offs. Currently, my mother still lives at home and has a caregiver at night, who gives her Sinemet every hour. She also has 6-8 hours of help during the day. This is working well, the only problem being the financial burden of so much care. In order to ease the financial burden, I am looking for alternative ways of handling the nights -- ideally this would entail eliminating the cost of a nighttime caregiver. Does anyone have experience with taking Sinemet in liquid by infusion, ie intravenously, or with the Sinemet patch? Any suggestions would be greatly appreciated. Best, Siobhan Roberts ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn