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Siobhan,

I'm no doctor by any means, but my sister took 25/100 Sinemet every two
hours around the clock until very recently, switching to a higher dose of
25/100 CR in the late evening, until resuming her usual doses in the
morning.  It is working very well, though not perfectly.  She was on only
the usual dosage, not the CR (Controlled Release, slower to work it's way
through your system and longer lasting), for so long that I can hardly
believe it took so long to try such a simple and effective change, but it
did.

Perhaps something along those lines might allow your mother to step back
from some of her night time help, and save some money that way.

Best of luck to you.

John in Flint, MI
-----Original Message-----
From: Siobhan Roberts <[log in to unmask]>
To: [log in to unmask] <[log in to unmask]>
Date: Thursday, January 13, 2005 2:10 AM
Subject: nighttime care


>I've joined the list on behalf of my mother. I hope to get her online and
an
>active participant soon. She has had Parkinsons for about 15 years,
>diagnosed when she was 47. At this stage, she still manages with optimism
>but things are getting difficult. In particular, I am interested in any
>information or ideas people have regarding coping with nights, or more
>generally with the need for constant assistance in taking medication due to
>the unpredictability of ons and offs. Currently, my mother still lives at
>home and has a caregiver at night, who gives her Sinemet every hour. She
>also has 6-8 hours of help during the day. This is working well, the only
>problem being the financial burden of so much care. In order to ease the
>financial burden, I am looking for alternative ways of handling the nights
>-- ideally this would entail eliminating the cost of a nighttime caregiver.
>Does anyone have experience with taking Sinemet in liquid by infusion, ie
>intravenously, or with the Sinemet patch? Any suggestions would be greatly
>appreciated.
>
>Best,
>Siobhan Roberts
>
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