FROM: Star Tribune (Minneapolis, MN) January 13, 2005, Thursday, Metro Edition SECTION: NEWS; Pg. 1B HEADLINE: Researcher noted for stem-cell work plans to leave 'U' BYLINE: Maura Lerner; Staff Writer Dr. Catherine Verfaillie, one of the pioneers of stem-cell research, is planning to leave the University of Minnesota to create a research center in her native Belgium. Verfaillie (pronounced Ver-fye) says she is stepping down as director of the university's Stem Cell Institute in two years for personal reasons, not because of any controversy over her field of research. "I've had my frustrations, but my decision has no ties to that," said Verfaillie, 47. "I'm not running away from anything." Verfaillie has been an outspoken defender of research on stem cells, including the most controversial kind, embryonic stem cells. She and other scientists hope that such cells eventually will be able to repair damage from a wide range of illnesses, from heart disease to Parkinson's. Yet she is best known for her work on adult stem cells, which do not involve embryos. She and her team were the first to show, in animal experiments, that stem cells from adult bone marrow could morph into heart, brain and other cells. Her departure is a blow to the university, which had fought hard to keep her from being lured away as her reputation flourished. "It's hard to fill Catherine's shoes," said Dr. Doris Taylor, a heart disease researcher who came to the university to work with Verfaillie. But, she said, "What Catherine has built here goes beyond Catherine Verfaillie. She's built a world-class stem-cell institute." For the next two years, Verfaillie plans to divide her time between Minnesota and Belgium as she oversees the creation of a stem-cell institute at the Catholic University of Leuven, her alma mater. She said that she still has family in Belgium, and that her decision was purely personal. "It's the right thing for me to do for reasons that are outside my scientific work and my professional life," she said. Verfaillie originally came to Minnesota from Belgium in 1987 for what she thought would be a six-month research program. She ended up staying for 17 years, making a name for herself - and the university - in one of the hottest fields of science. In 2000, she was named one of the nation's 10 leading innovators in science and technology by U.S. News and World Report. And she won a prestigious endowed chair at the university in 2001. Her work has been cited by both sides in the political debate over stem-cell research. In 2002, Sen. Sam Brownback, R-Kan., suggested that her work on adult cells proved there's no need to use stem cells from embryos. But Verfaillie said it's too soon to know whether adult cells will work as well as embryonic ones. She plans to do both kinds of research in Belgium. "I think she's helped us to understand that we shouldn't be closing the door on other kinds of stem-cell research yet," said Dr. Frank Cerra, senior vice president for health sciences at the university. Verfaillie plans to retain her ties to the university after she leaves, as a part-time faculty member and through a series of scientific collaborations. "I know - there's a big ocean in between," she said, "but e-mails go as quickly from here to Belgium as they go one floor down." Maura Lerner is at [log in to unmask] ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn