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Alison, Several years ago, I was taking 25/100 Carbo-Levodopa(immediate-release generic Sinemet) and got to the point where I was taking one every hour to feel normal. My neurologist switched me to 50/200 Carbo-Levodopa (Extended release) with 200 mg. Comtan. I take that four times a day, (7:am, 11:am, 3:pm and 6-7:pm). I'm also careful about separating my intake of protein and levodopa. There seems to be less conflict with protein if I choose it from a lower rung of the food chain (eggs, cheese, beans or nuts instead of beef or bacon). This regime has kept me feeling mostly normal for some time. Recently, I've noticed it takes longer to ramp up to "ON" and I experience some shortness of breath and diskenesia(sp?) while that's happening. NOTE: I'm only sharing my experiences. You or your mother should check with your neurologist to see if any of this is relevant to your situation. Cheers, George. Alison <[log in to unmask]> Sent by: Parkinson's Information Exchange Network <[log in to unmask]> 02/11/05 01:48 PM Please respond to Parkinson's Information Exchange Network <[log in to unmask]> To [log in to unmask] cc Subject Re: Question re: Comtan, Sinemet, Stalevo and Requip Alison, My mom is now on the Stelevo and Mirapex now. I am under the impression that Stelevo is just the Comtan and Sinemet together. Her "on" times are becoming less frequent and the stelevo isn't working like it first did. She has terrible Restless Legs Syndrome and sometimes that is her biggest concern so her Dr.put her on Mirapex. She also has anxiety attacks so she takes Ativan which she probably is addicted to, but at her age who cares if it makes her feel any relief at all. I can't say how much the change in meds helps, but she can't walk at all without them. Alison (luv that name) ----- Original Message ----- From: "Alison Landes" <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, February 10, 2005 8:33 AM Subject: Question re: Comtan, Sinemet, Stalevo and Requip > My sister's computer is being repaired. She asked me to submit question to > ListServe about medication. > > She has been taking Sinemet and Requip with a lot of off time. > Neurologist is going to start her on Stalevo with the Requip. > > She has not taken Comtan with Sinemet and Requip. > Nor has she taken Sinemet CR with the Requip. > > Does anyone have any point of reference with the above? > > Thank you. > > > Alison Landes > Founder/ President > Take Charge! Cure Parkinson's, Inc. > 1489 W. Palmetto Park Road Suite 442 > Boca Raton, Florida 33486 > Tel: 561.620.1970 > Fax: 561.488.5726 > E-mail: [log in to unmask] > Web site: _www.cureparkinsons.org_ (http://www.cureparkinsons.org/) > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn