uh-uh -- apokyn works for the OTHER end of the symptoms; the OFF, hypomobility times; the freeze. it would have a terrible effect if used while a PWP is at the opposite side of the spectrum, i.e., dyskentic and/or writhing. http://www.fda.gov/bbs/topics/ANSWERS/2004/ANS01284.html apomorphine has been available in israel for a while now, but only recently (i believe since the FDA approved it in the US) has become available in a new form of packaging which makes it user-friendly and not as off putting as "sticking a needle" might sound. it's probably more reminiscent of the discreet insulin 'pumps' for diabetics. and it truly works wonders to get a person out of a FREEZE. alas, doesn't last long -- say 20 minutes or so -- but gives you enough of a window to have the next oral dose kick in. but here's a curious (or shocking, really) thing -- had to take my israeli-american PWP who's being treated in israel, to the movement disorder center at mount sinai hospital in new york city. you'd think, doesn't get any more cutting-edge than that. well, surprise, surprise -- they've never seen apokyn at work! yes, they know of its existence, but apparently the stuff is simply unavailable here. :( hope this helps, ariela ==== > Yes, Apomorphine has been available here in the UK for several years now, I > know two fellow sufferers of PD who used it. In both cases it did work well, > and almost instantly, but, and it's a big but, both of these people > experienced extreme end of dose side effects in the form of severe > dyskenesia, uncontrollable writhing and twisting of limbs . It was enough > for me to regard this drug as one to avoid . > > Nigel, age 50 , dx 34 > ----- Original Message ----- > From: "M.Schild" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Tuesday, February 15, 2005 7:21 AM > Subject: Re: APOKYN > > > >> I HOPE EVERYONE WILL BE AS EXCITED ABOUT THIS AS I AM. ASK THEM TO SEND > >> YOU A COPY OF THE VIDEO. IT'S GREAT. APOKYN (APOMORPHINE HYDROCHLORIDE ) > > > > > > It has been used in Europe for a while now. The injections work quickly > > but > > the effect doesn´t last long. One can have it deliverred through the day > > by a > > ´pump' also > > Maryse cg John 75,5 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn