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Arelia - i was on amantadine and sinemet (and mirapex and one other agonist) for many years . I was switched to stalevo in april or so and "crashed" in august. Hallucinationsm, sleepwalking, reduceed cognition and both dyskinesia and freezing all resulted. I don'tr know -- and never will know -- what to blame. but I am now back on sinemet (900 mg instead of the 250 i used to be on) and no more stalevo, amantadine or any othr agonist. I still freeze a lot, and my dyskinesia is sometimes bad, but the mental stuff has gone. I have changed movement disorder specialists but I am not sure that was wise. I was so frustrated it seemed time for a change. I think my comments are no help at all as I have not resolved anything, but I have been there Nancy deGrazia. ariela wrote: >rick, > >a new movement disorder neurologist we've now been seeing at mount sinai in new york has told us that amantadine is the drug of choice for dealing with dyskinesia. it's the first i hear this take about this little-used drug.... but we're still keeping this option open as my PWP is now trying stalevo (after 4 years on sinemet + requip). he's having an awful time just getting calibrated -- he moves instantaneously between long and painful freezes to awful states of badly spastic dyskinesia. there's just never a simple 'quiet,' 'calibrated' time. it goes without saying that the dosages and frequency have been tweaked and re-tweaked, to not much avail... :( > >does it sound familiar to you, or anyone on the list? can anyone please share what you do/have done/know about it? ( > >many thanks, >ariela > >==== > > > >>But I just figure it might be worth a little extra pain in order to put off those nasty >>diskenesias.... >> >>Enjoy! >>Rick McGirr >> >> > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: mailto:[log in to unmask] >In the body of the message put: signoff parkinsn > > > > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn