Michael J. Fox and Parkinson's Disease Your Guide, Mary Kugler <http://rarediseases.about.com/mbiopage.htm> From Mary Kugler <http://rarediseases.about.com/mbiopage.htm>, Your Guide to Rare / Orphan Diseases <http://rarediseases.about.com/>. *FREE* Newsletter. Sign Up Now! <http://rarediseases.about.com/gi/pages/mmail.htm> Exact causes still a mystery Between one and one-and-a-half million Americans are affected by Parkinson's disease, a disorder of the central nervous system. "Parkinson's" is the overall term for at least six different categories <http://rarediseases.about.com/library/weekly/blcategories.htm>of the disorder, which usually affects people age 50 or older. About 10-20% of people with Parkinson's are diagnosed before age 50; only half of these people are diagnosed before age 40. This is called juvenile Parkinson's. Michael J. Fox <http://clk.about.com/?zi=1/XJ&sdn=rarediseases&zu=http%3A%2F%2Fus.imdb.com%2Fname%2Fnm0000150%2F>, diagnosed at age 38, is in this category. *Possible causes* People with Parkinson's disease have a shortage of a chemical that affects movement (called dopamine) in their brains. It appears that changes in the cells of the substantia nigra, the area of the brain that produces dopamine, are at fault. Sponsored Links All About Parkinson'sEverything You Really Need To Know About Parkinson's Disease.www.AllAboutParkinsons.com <http://pagead2.googlesyndication.com/pagead/iclk?adurl=http://www.allaboutparkinsons.com&sa=l&ai=BSDNfrDdRQo_1K6LmigHAkPCyCJD74gnG0fmkAcCNtwHQhgMQARgBIKil9wEoCEi6OaABy52K_wOqARVwcmltZWRpYV9yYXJlZGlzZWFzZXOyARZyYXJlZGlzZWFzZXMuYWJvdXQuY29tyAEB2gE7aHR0cDovL3JhcmVkaXNlYXNlcy5hYm91dC5jb20vb2QvcmFyZWRpc2Vhc2VzcC9hLzA2MDcwMC5odG0&num=1&client=ca-primedia-premium_js> Stop Parkinson's DiseaseTreat and Eliminate Suffering Now Doctor Recommended All Naturalwww.trustedaloeproducts.com <http://pagead2.googlesyndication.com/pagead/iclk?sa=l&ai=BxD9irDdRQo_1K6LmigHAkPCyCKD97QbwjO2UAcCNtwHwhA4QAhgCIKil9wEoCEivOaoBFXByaW1lZGlhX3JhcmVkaXNlYXNlc7IBFnJhcmVkaXNlYXNlcy5hYm91dC5jb23IAQHaATtodHRwOi8vcmFyZWRpc2Vhc2VzLmFib3V0LmNvbS9vZC9yYXJlZGlzZWFzZXNwL2EvMDYwNzAwLmh0bQ&num=2&adurl=http://www.trustedaloeproducts.com&client=ca-primedia-premium_js> Parkinson's or is it NPH?Parkinson's has similar symptoms to Normal Pressure Hydrocephalus.www.allaboutNPH.com <http://pagead2.googlesyndication.com/pagead/iclk?sa=l&ai=BHPR-rDdRQo_1K6LmigHAkPCyCPqKeuCPQsCNtwGQvwUQAxgDIKil9wEoCEifOaoBFXByaW1lZGlhX3JhcmVkaXNlYXNlc7IBFnJhcmVkaXNlYXNlcy5hYm91dC5jb23IAQHaATtodHRwOi8vcmFyZWRpc2Vhc2VzLmFib3V0LmNvbS9vZC9yYXJlZGlzZWFzZXNwL2EvMDYwNzAwLmh0bQ&num=3&adurl=http://www.allaboutnph.com&client=ca-primedia-premium_js> How these changes happen is not precisely known; theories include accelerated aging, genetic susceptibility, and environmental factors, among others. Most likely Parkinson's disease is caused by a combination of these things. *Medical treatment* Treatment of Parkinson's disease has traditionally been with medication that can be made into dopamine in the brain (Sinemet), or by drugs that seem to affect the use of dopamine in the brain (Symmetrel, Eldepryl). Newer drugs, called dopamine agonists (Parlodel, Permax, Mirapex, Requip), activate dopamine-sensitive brain cells. Surgical treatments One technique being investigated is high-frequency stimulation of a part of the brain called the subthalamic nucleus. This is known as deep brain stimulation <http://rarediseases.about.com/cs/movementdisorders/a/020902.htm>. Brain tissue transplants using genetically-altered cells, fetal tissue, or pig tissue introduce cells to produce dopamine. New techniques for thalamotomy and pallidotomy, which destroy the "trouble-causing" cells in the brain using an electrode, are being developed. *Michael J. Fox* Michael J. Fox has established The Michael J. Fox Foundation for Parkinson's Research <http://clk.about.com/?zi=1/XJ&sdn=rarediseases&zu=http%3A%2F%2Fwww.michaeljfox.org>. He has spoken out in favor of stem cell research and has worked tirelessly to raise money for research. The Foundation Web site states, "Fox wholeheartedly believes that if there is a concentrated effort from the Parkinson's community, elected representatives in Washington, DC, and (most importantly) the general public, researchers can pinpoint the cause of Parkinson's and uncover a cure by 2010." Important disclaimer information about this About site. <http://rarediseases.about.com/gi/pages/mcopyrt.htm> Suggested Reading Categories of Parkinson's disease <http://rarediseases.about.com/library/weekly/blcategories.htm> Deep Brain Stimulation <http://rarediseases.about.com/cs/movementdisorders/a/020902.htm> Most Popular Video <http://home.about.com/homegarden/video/craftroom.htm?ap=1> Bathroom Decoration Ideas <http://home.about.com/homegarden/video/bathroom.htm?ap=1> Tag Sale Tips <http://home.about.com/homegarden/video/tagsale.htm?ap=1> Creating a Craft Room <http://home.about.com/homegarden/video/craftroom.htm?ap=1> Fashion for Special Occasions <http://home.about.com/style/video/specialoccasions.htm?ap=1> Women: Building a Wardrobe <http://home.about.com/style/video/womenwardrobe.htm?ap=1> See other videos at About.com <http://video.about.com> Sponsored Links Parkinsons Long Term CareFree guide for medical, custodial, and support service for Parkinson'swww.DestinationRx.com <http://pagead2.googlesyndication.com/pagead/iclk?sa=l&ai=BQh5VrDdRQo_1K6LmigHAkPCyCKrMzwewkL8HwI23AeDFCBAEGAQgqKX3ASgISKg5qgEVcHJpbWVkaWFfcmFyZWRpc2Vhc2VzsgEWcmFyZWRpc2Vhc2VzLmFib3V0LmNvbcgBAdoBO2h0dHA6Ly9yYXJlZGlzZWFzZXMuYWJvdXQuY29tL29kL3JhcmVkaXNlYXNlc3AvYS8wNjA3MDAuaHRt&num=4&adurl=http://www.destinationrx.com/promotions/specialtyplanners/default.asp%3Fpg%3D1021&client=ca-primedia-premium_js> Parkinson's Disease InfoInformation about Parkinson's and Related Conditions OnlineParkinsons.Medical-Information.org <http://pagead2.googlesyndication.com/pagead/iclk?sa=l&ai=BMgCVrDdRQo_1K6LmigHAkPCyCNOlwQa3ncCQAcCNtwHQhgMQBRgFIKil9wEoCEiuOaoBFXByaW1lZGlhX3JhcmVkaXNlYXNlc7IBFnJhcmVkaXNlYXNlcy5hYm91dC5jb23IAQHaATtodHRwOi8vcmFyZWRpc2Vhc2VzLmFib3V0LmNvbS9vZC9yYXJlZGlzZWFzZXNwL2EvMDYwNzAwLmh0bQ&num=5&adurl=http://parkinsons.medical-information.org&client=ca-primedia-premium_js> Parkinsons Success CasesYou no longer have to live with Parkinsons. Free video tour.www.sanoviv.com <http://pagead2.googlesyndication.com/pagead/iclk?adurl=http://www.sanoviv.com/content/view/73/46/&sa=l&ai=BOSyyrDdRQo_1K6LmigHAkPCyCMzc4wjc1c2iAcCNtwHQhgMQBhgGIKil9wEoCEi4OaABoej9_gOqARVwcmltZWRpYV9yYXJlZGlzZWFzZXOyARZyYXJlZGlzZWFzZXMuYWJvdXQuY29tyAEB2gE7aHR0cDovL3JhcmVkaXNlYXNlcy5hYm91dC5jb20vb2QvcmFyZWRpc2Vhc2VzcC9hLzA2MDcwMC5odG0&num=6&client=ca-primedia-premium_js> Dr. Enrico FazziniThe Parkinson's Doctor Medication Adjustment Specialistwww.theparkinsonsdoctor.com <http://pagead2.googlesyndication.com/pagead/iclk?sa=l&ai=B1W2ZrDdRQo_1K6LmigHAkPCyCLq41AWu48uOAcCNtwHQuxsQBxgHIKil9wEoCEilOaoBFXByaW1lZGlhX3JhcmVkaXNlYXNlc7IBFnJhcmVkaXNlYXNlcy5hYm91dC5jb23IAQHaATtodHRwOi8vcmFyZWRpc2Vhc2VzLmFib3V0LmNvbS9vZC9yYXJlZGlzZWFzZXNwL2EvMDYwNzAwLmh0bQ&num=7&adurl=http://www.theparkinsonsdoctor.com&client=ca-primedia-premium_js> Parkinson's DiseaseTreatment Options for Parkinson's - Trustworthy, Current Reportwww.medifocus.com <http://pagead2.googlesyndication.com/pagead/iclk?adurl=http://www.medifocus.com/guide_detail.asp%3Fgid%3DNR013%26a%3Da%26assoc%3DGoogle%26keyword%3Dparkinsons&sa=l&ai=BpwsjrDdRQo_1K6LmigHAkPCyCNSbmQaut42TAcCNtwHQhgMQCBgIIKil9wEoCEifOaABss-7_wOqARVwcmltZWRpYV9yYXJlZGlzZWFzZXOyARZyYXJlZGlzZWFzZXMuYWJvdXQuY29tyAEB2gE7aHR0cDovL3JhcmVkaXNlYXNlcy5hYm91dC5jb20vb2QvcmFyZWRpc2Vhc2VzcC9hLzA2MDcwMC5odG0&num=8&client=ca-primedia-premium_js> ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn