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Raj, Thanks for the very detailed reply. Curious - why do you take Tumeric in stead of Curcumin? Nick R.Rajaraman wrote: >WARNING: > I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION. I DO >THIS AFTER A THOROUGH LITERATURE SURVEY. > I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY ADVICE TO >ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A >QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING CURRENTLY. > >Hi Nick & Oanh: > Anybody who knows about the action of sinamet, will opt to stay out of >it as long as possible. That was and is my whole aim even today. It is >unfortunate that no new and useful medication has been invented for the past >several decades. I visited my neuro last week. The intern that saw me for >almost 40 minutes was trying to push sinemet on me very hard. He sounded >worse than the medical sales rep. He insisted that sinemet does not cause >dyskenesia! > When I told him that Cox-2 inhibitor is important for slowing the >progression of PD, he didn't even know about it. That is the kind of >younger generation of doctors we are training! After the chief had a talk >with me, he said more or less the same thing. However, at the end of my >visit, another intern came with a questionnaire that she was studying. This >was about the bad side effects caused by sinamet and the patients aptitude >with regard to taking sinemet. Both the interns were contradicting each >other. > To cut the long story short, I still was not convinced enough to take >sinemet. I have determined to sty out of it as long as I can manage. >Therefore, I am still pursuing my multiprong attack and hope I can solve my >problems. However, I must say that I have been so far lucky to drastically >slow down the progression of PD. I cannot still say I have stopped the >progression completely. > Here are the things that I take everyday: > > Morning: > 20 Min yoga and exercise* > Dr. Paneri's medication* > Synthroid (for hypothyroidism) > Acetyl-l-carnitine** > Folic acid for BP & nerves > B12 > Celebrex 100 mg* > Brain essentials from Swanson's nutritionals* > Co E Q 10 for PD and heart * > Green tea capsule > MIX of blue berry and pomogranate juice (for Pd and heart) > bran cereal + almonds and walnuts > >Lunch time: > Dr. Paneri's medication > Acetyl-l-carnitine > Atacand (for Blood Pressure) > L-Carnosine** > Co E Q10 > Chondroitin/glucoasmine caps. > Multivitamin > Omega 3 oil or salmon oil on alternate days or when I don't consume >salmon for a few days.. > Brain essentials* > Light lunch with fruits and juices > >Supper time: > Dr. Paneri's medication > Aceyl-l-carnitine > Resveratrol** > Brain essentials > Turmeric caps 400 mg (for PD and general health of nerves) > Supper with salads, fish or chicken no rice (low carb diet) > >before bed time: > Atacand for BP. > Listen to the Mind Aerobics tape** > >*THese items I find very useful. >** These items have anti-aging, anti-inflammatory, anti-oxidnt, >neuroprotective and neuro regenerative properties. These should be consumed >by everybody for general health. > > In general, I avoid beef, rice, and white bread, when ever possible. > I consume plenty of stuff like spinach and stawberries (both great for >PD). I make it a point to take a variety of fruits, not necessarily all at >the same time. The idea is to consume anti-inflammatory, neuroprotective, >neuro-regenerative, and antioxidants as much as possible. >WARNING: > I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION. I DO >THIS AFTER A THOROUGH LITERATURE SURVEY. > I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY ADVICE TO >ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A >QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING CURRENTLY. > I was diagnosed in 1999. It too me two yearss bfore I understood the >seriousness of PD and he woes of allopathic PD medications. I wish I >started on my protocol much earlier. > However, I must say that my friends, including doctors, and my two >sons, who are doctors themselves, tell me that I look a lot better than I >use to a couple of years ago. In fact, a medical doctor friend of mine was >so impressed with my health improvement, he is prescribing the same things >to his patient, who did not respond well of the conventional medicines. > I must add that I am painfully aware that I am not out of the woods yet. >If everything else fails, I can always starting on sinemet, which would be >my last option. I am still on constant look out for alternative medications >for my PD. > > I hope I have answered your questions. > Wishing you all the best. > Raj >******************** >----- Original Message ----- >From: "Nick & Oanh" <[log in to unmask]> >To: <[log in to unmask]> >Sent: Saturday, April 02, 2005 6:19 AM >Subject: Curcumin inhibits neuronal cell death > > > > >>Hi Raj, >>Been following your posts, and the novel way you are combating PD. >> >>Would you be so kind and let us know what you are taking now, and how >>well it's working for you? >> >>Thanks in advance, >>Nick >> >>Brightline wrote: >> >> >> >>>Hi Everybody: >>> I was aware that curcumin, an active component of the Indian spice & >>> >>> >condiment, turmeric, has some protective action against PD and also has >certain cancer-killing effect. The consumption of turmeric is thought to be >one of the reasons why PD is rare in Indian population. However, I did not >know the mechanism of its action. Recently, I ran into some interesting >references that claim curcumin inhibits the death of dopaminergic neurons in >the MPP+ Parkinson's disease model (Neuropharmacology 2002, 42, 1056-64) by >inhibiting an enzyme that triggers cell death or apoptosis. I also found >some references to the effect that Omega 3 Fatty Acid (good for the heart >too) also acts in a similar fashion > > >>> Therefore, I have added these two in my arsenal against the >>> >>> >advacement of PD. This is for your info only. > > >>> Please talk to your physician before you change anything. >>> Wish you all the best. >>> Raj >>>********* >>> >>>---------------------------------------------------------------------- >>>To sign-off Parkinsn send a message to: >>> >>> >mailto:[log in to unmask] > > >>>In the body of the message put: signoff parkinsn >>> >>> >>> >>> >>> >>---------------------------------------------------------------------- >>To sign-off Parkinsn send a message to: >> >> >mailto:[log in to unmask] > > >>In the body of the message put: signoff parkinsn >> >> > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: mailto:[log in to unmask] >In the body of the message put: signoff parkinsn > > > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn