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NIH knocks stem cell laws
 The Washington Post

April 8, 2005

WASHINGTON - Breaking with a tradition of deference to top administration
officials, several institute directors at the National Institutes of
Health on Wednesday went public with their distaste for current federal
restrictions on human embryonic stem cell research.

Their comments, in writing and in testimony before the subcommittee on
Labor, Health and Human Services and Education, reflect festering
frustration over the policy initiated by President George W. Bush in
2001.

"Progress has been delayed by the limited number of cell lines," wrote
Elizabeth Nabel, the new director of the National Heart, Lung and Blood
Institute. "The NIH has ceded leadership in this field."

The science, which aims to develop treatments for a range of diseases
using cells from five-day-old human embryos, stirs controversy because
embryos are destroyed in the process. Under the Bush policy, researchers
cannot use federal funds to conduct research on stem cells isolated after
Aug. 9, 2001. That keeps taxpayers from contributing to embryo
destruction but also keeps the federal research enterprise from exploring
newer and in some respects more promising colonies, or lines, of cells.

This summer, Congress is expected to consider legislation that would
allow federal funding of research using embryos slated for destruction at
fertility clinics - a change the administration has said it opposes and
which NIH leaders have until now avoided addressing. But several of them
made clear their antipathy for the status quo Wednesday.

Nora Volkow, director of the National Institute on Drug Abuse, complained
that gaining access to the relatively few approved stem cells lines is
"complicated and expensive." James Battey, director of the Institute on
Deafness and Other Communication Disorders, also was unusually blunt.

"The state of the science is moving very, very rapidly," Battey
testified, drawing attention to new lines of cells developed in Chicago
that show biomedical promise. "These cell lines, however, were all
created after Aug. 9, 2001, and are therefore ineligible for federal
funding." Battey has applied for a job with a newly formed California
stem cell research institute.

"If they're going to be destroyed [anyway], where is the moral issue?"
Sen. Arlen Specter (R-Pa.) asked NIH director Elias Zerhouni, referring
to the legislative proposal to allow funding of research on embryos
destined to be discarded.

"I think you'll have to ask that from those who hold that view," Zerhouni
replied.

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