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Diane Nicolaou wrote: >I am having jaw surgery later this month and will not be able to open my >mouth or jaws for 3 weeks after. I am not so concerned about being in intensive >care on a respirator immediately afterwards or being on a liquid diet for 3 >weeks but how am I to take my Sinemet CR and mirapex? I really rely on them >every 3 1/2 to 4 hours. >The Doctors say I will have to crush all meds and my Neuro says I can do >that it just won't last as long. The pharmacy tells me there is no liquid >sinemet. This has me worried. Any advice? and how do I make sure they give me my >meds while I am hospitalized? I'm thinking this is going to be a struggle. > It is possible to "liquefy" sinemet. Indeed because it acts more quickly people have used it for rescue. This is true especially if it is dissolved in sugar water. So you can certainly do that for the sinemet. One caveat is that it acts more quickly and may wear off more quickly. But the thing to do is to try the meds in liquid form before the operation and if necessary to adjust the timing and dosage. You can make a "stock" solution but it keeps only for about a day. So it would be prudent to prepare it at least twice a day. Dissolving will negate the delay effect of the CR sinemet but you can create the effect by sipping the "juice" at regular intervals say every half hour. You must estimate the dosage to make it roughly equivalent to taking Sinemet in tablet form Maybe using a shot glass to measure the liquid would be a good idea. But sipping is a good idea anyway because you even out the dosage. As for the Mirapex, try to do the same and see if it is effective dissolved --- again before the operation. I don't think there is a downside to trying. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn