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Dear Jann, Sorry that my response to your inquiry is somewhat delayed. sometimes I get behind on the messages on this List and maybe the suggestion of DBS surgery has already been mentioned. Have you inquired into DBS? You say that your dad has been taking Sinemet for quite a long time. It is possible that he is to the point that the medication can no longer be as effective to control his symptoms as it once was. I know that DBS is a rather drastic option and that there are both good and bad outcomes. I hope that you have access to advice from knowledgeable doctors as to whether your dad would be a good candidate for this procedure. As I said earlier, maybe I'm out of the loop on the responses that you've received to date and this could have already been mentioned. Dee ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn