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Columbia University Launches Multi-Year Campaign to Support Stem Cell
Research

i-Newswire,
June 20, 2005
- Columbia University Medical Center researchers are at the forefront of
an extraordinary movement to revolutionize medical approaches to
therapeutics through its Stem Cell Initiative. Columbia's leadership in
developmental biology, neuroscience research, transplantation, and cell
replacement therapy uniquely positions the university to push stem cell
research forward, and more than 40 CUMC researchers are currently
conducting leading stem cell studies.

“This initiative will provide our researchers with the resources
necessary to fully realize the potential of stem cells,” said Gerald D.
Fischbach, M.D., executive vice president of Columbia University Medical
Center and dean of the faculty of medicine at Columbia's College of
Physicians and Surgeons. “Columbia continues to be a leader in this
revolutionary health technology that holds the promise to benefit people
suffering from a wide variety of debilitating health problems.”

Federal restrictions on human embryonic stem cell research funding and
lagging state funds have limited available government support for this
emerging and promising research, prompting CUMC to reach out to the
private sector with this crucial stem cell initiative.

CUMC researchers are currently exploring the vast potential of stem cells
to treat a wide range of illnesses, including Parkinson's disease,
amyotrophic lateral sclerosis ( ALS ), diabetes, pancreatic cancer,
leukemia, stroke and other diseases of the nervous system, liver, eye,
skin, and heart. Beyond replacement therapy, the use of stem cells as a
research tool will lead to new insights regarding mechanisms that control
the onset and progression of disease. Stem cells will also be useful as
targets in drug discovery. Current stem cell research projects at CUMC
include:

-- Examining the development, function and survival of dopamine neurons,
which are lost in patients with Parkinson's disease, focusing on
developing replacement cells or a model for investigation of genetic
forms of the disease

-- Developing an experimental procedure that expands the use of umbilical
cord blood in transplantation for childhood leukemia and solid tumor
patients

-- Implanting stem cells that turn into insulin-producing cells to fight
the growing epidemic of diabetes

-- Studying the biology of stem cells that produce new neurons in the
normal adult mammalian brain as a key to understanding brain repair and
neural pathologies.

-- Generating specific spinal and brain nerve cells from embryonic stem
cells

-- Developing potential new cancer remedies

“In the last several years scientists have managed to unlock many of the
secrets behind stem cells and their remarkable ability to develop into
different kinds of cells, but there is still much to learn,” said Asa
Abeliovich, M.D., Ph.D., whose research is focused on developing stem
cells to replace dopamine neurons lost in Parkinson's disease or models
to mimic the degeneration process. “The resources provided by Columbia's
stem cell initiative will help us answer those questions and translate
this research into practical applications for many our most devastating
diseases.”

The initial $50 million for the Columbia Stem Cell Initiative will enable
Columbia to outfit a new stem cell center, construct a state-of-the-art
facility to produce cells for experimental and therapeutic use, and
establish a separate laboratory dedicated to growing new human embryonic
stem cells for new studies. It will also support the recruitment and
retention of internationally renowned stem cell biologists and establish
endowments for professorships for Columbia's stem cell physicians and
scientists as well as scholarships for doctoral candidates and
post-doctoral fellows focused on stem cell studies.

NOTE: Additional CUMC stem cell experts can be found at the Stem Cell
Consortium website at www.healthsciences.columbia.edu/hs/stemcell

umbia University Medical Centervides international leadership in basic,
pre-clinical and clinical research, medical education, and health care.
The medical center trains future leaders in health care and includes the
dedicated work of many physicians, scientists, nurses, dentists, and
other health professionals at the College of Physicians & Surgeons, the
School of Dental & Oral Surgery, the School of Nursing, the Mailman
School of Public Health, the biomedical departments of the Graduate
School of Arts and Sciences, and allied research centers and
institutions. With a strong history of some of the most important
advances and discoveries in health care, its researchers are leading the
development of novel therapies and advances to address a wide range of
health conditions. http://www.cumc.columbia.edu


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Published on:
2005-06-20
http://i-newswire.com/pr26053.html

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