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 Forty-one consecutive patients with suboptimal results of DBS surgery over
a 24-month period were reviewed. Issues related to inadequate pre-operative
screening, surgical and device-related complication and
programming/medication adjustments were factors in the evaluation. They
report that with appropriate specific intervention, 51% of patients who
presented complaining of "failed" DBS procedures ultimately had good
outcomes.

Source:  http://archneur.ama-assn.org/cgi/content/full/62.8.noc40425v1



While 51% is still "good" results, this is another indication of why patient
groups need to be watchdogs for newly-approved surgical procedures and to
keep others informed of the latest studies.  The Parkinson Pipeline Project
is such a group.  Composed almost entirely of PD patients, we are doing some
exciting and vital work on seeking better treatments and ultimately - a
cure.  Keeping the PD community informed is one of our goals.  (Check out
our website at www.pdpipeline.org ).



The Reuter's AlertNet news report is given in part below:

http://www.alertnet.org/thenews/newsdesk/N13645969.htm



Brain stimulation therapy can be ineffective-study

13 Jun 2005 21:59:15 GMT



CHICAGO, June 13 (Reuters) - Placing electrodes in the brain to calm tremors
failed to help some patients with Parkinson's disease and other movement
disorders because they were not good candidates for the treatment or the
devices were poorly implanted, a study said on Monday.



The treatment, called deep brain stimulation surgery, is approved in the
United States for the treatment of Parkinson's, essential tremor and the
movement disorder dystonia.



 *   *   *

Medtronic Inc. <MDT.N> is the only company currently on the U.S. market with
the technology, which involves implanting a device that delivers mild
electrical stimulation to block the brain signals that cause tremor.



However, a number of medical device companies are investing heavily in
neurostimulation technology, and the market for all neuromodulation
products, which include devices to manage pain, is expected to reach $1.5
billion this year, according to a study by Susquehanna Financial Group.



A Medtronic spokeswoman did not have an immediate comment on the study. The
devices to date have been implanted in 30,000 patients worldwide, Medtronic
said.[/i]



Peggy




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