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My mom's doctor is increasing her sinemet dose from three times daily to four times daily in hopes that the increase will help with her afternoon agitation. I will be curious to see if it does. It still seems to me like we might need to add some anti-anxiety meds as well but we will see. Mom also seems to be catching a cold. I have her using some saline nose drops. Does anyone know how vitamin C interacts with sinemet? Normally, I would give her some vitamin C powder in juice when she seems to be catching a cold. Thanks, Peggy ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn