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Amanda, Apparently not for about 10-15 years - which would explain why patients with no natural ldopa being produced in their brains can still convert sinemet to dopamine in their brains, however imperfectly, for many years. But I will look into this more closely and see what's what. Greg Amanda Phillips <[log in to unmask]> wrote: Won't the new additions to the brain just die of whatever killed the original cells ? Presumably you have to keep topping up? ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn "Willy Loman never made a lot of money. His name was never in the paper. He's not the finest character that ever lived. But he's a human being, and a terrible thing is happening to him. So attention must be paid...Attention, attention must finally be paid to such a person." - Arthur Miller - Death of a Salesman ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn