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Statin and aspirin may reduce risk of brain diseases
 By Hasnita A Majid, Channel NewsAsia




http://www.channelnewsasia.com/stories/singaporelocalnews/view/175438/1/.html






Statin and aspirin are currently used to treat heart diseases.

 But researchers say these drugs, which have anti-inflammatory properties,
also seem to lower the risk of Alzheimer's and Parkinson's diseases as well.

 This is because their findings suggest the drugs can reduce the inflammation
of cells that support the neurons - which are message-carrying cells in the
brain.

 Alzheimer's and Parkinson's diseases occur when brain cells degenerate.

 Professor Caleb E Finch, a neurologist from the University of Southern
California, said: "In the same communities where these (drugs) have been
successful in reducing heart attack by 30 percent or more, the risk of
Alzheimer's disease is lower. So I think - well, many of us think - that the
inflammatory processes in vascular diseases and Alzheimer's diseases are very
similar."

 Prof Finch says this finding is important, to ensure that stem cell
transplants to replace ageing neurons are successful.

 However, he adds that prescribing statin or aspirin to those who are
susceptible to brain diseases as a preventive step is not advisable as more
research needs to be done.

 With this knowledge, his team is looking at developing a drug which may have
dual function - slow down or prevent Alzheimer's and Parkinson's diseases as
well as prevent heart disease.

 Prof Finch's research finding is just one of the papers presented at the
Keystone Symposia on stem cell biology.

 Over the next few days, experts at the symposium in Singapore are expected to
discuss further the latest research findings and breakthroughs in stem cell
therapy.

 They will discuss especially how advances in the understanding of stem cell
biology can be applied to cancer cells. - CNA/ir

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